MOTS-C

MOTS-C Research Compound

MOTS-C (Mitochondrial Open reading frame of the 12S rRNA type-c) is a mitochondrial-derived peptide encoded in mitochondrial rather than nuclear DNA. In metabolic research it is studied as a signaling molecule involved in energy homeostasis and cellular crosstalk between mitochondria and the nucleus, often described as an "exercise mimetic" in cell-culture models.

Laboratory Research Focus

MOTS-C is used in cell-culture models to examine the folate–methionine cycle and AMPK pathway activation. Researchers study its effects on glucose uptake, mitochondrial biogenesis and substrate oxidation in skeletal-muscle and adipocyte models.

• AMPK signaling Examined as an upstream modulator of AMPK activation in vitro.
• Glucose uptake Studied in skeletal-muscle and adipocyte models of substrate utilization.
• Mitochondrial biogenesis Applied in models of mitochondrial function and energy production.

Why BondPep

• Third-party analytical release Every batch runs reverse-phase HPLC with UV detection and ESI-MS identity check by an independent laboratory before it enters inventory.
• Lot records retained per batch Each vial links to its own batch number; the corresponding HPLC and ESI-MS record is provided on request from support.
• Cold-chain handled Material is climate-controlled from receipt to dispatch, with insulated packaging for temperature-sensitive orders.
• Same-day dispatch In-stock orders leave the facility within 24 hours on business days, tracked to your destination.

Reconstitution & Storage

Reconstitute with sterile bacteriostatic water before laboratory use. Allow the diluent to reach room temperature and inject it slowly down the inner vial wall; do not shake or vortex. Roll the vial gently until the solution is clear and uniform.

Store unopened lyophilized powder at −20°C, protected from light. Once reconstituted, keep refrigerated at 2–8°C and use promptly. Handle with appropriate PPE in a certified laboratory setting.

Product Specifications

• Nomenclature MOTS-C, Anti-Aging research compound
• Package 10-vial box, sealed glass vial
• Physical form White lyophilized powder
• Purity analytics ≥99% (third-party verified)
• Preparation Reconstitute with bacteriostatic water before laboratory use
• Storage −20°C lyophilized; 2–8°C after reconstitution

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